Avida Serena 4 Bedroom Vacation Rental With Gulf Access in Cape Coral, FL

Home Rental in Cape Coral Florida

Picture Windows in Screened in Lanai offer Fantastic Views of the Canal and Sunsets

The Extended Dock with Sitting Area offers Plenty of Space to Enjoy the Waterview or Turn on the Fireplace

Four-bedroom home in Cape Coral, FL on a wide canal basin with direct Gulf access, a heated pool and jacuzzi, and walkable dining and shops—an ideal place to stay for families or groups up to 8.

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Rates from

$231 / night

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Avida Serena is a 4-bedroom, 3-bath waterfront home in Cape Coral, Florida, set on a wide canal basin with direct Gulf access in under 20 minutes. The 2,200-square-foot layout sleeps up to 8 and includes a western-facing lanai positioned for sunset views over the water. Two main suites with en-suite bathrooms add privacy for multi-room stays, and the home includes a boat dock with a boat lift available.

Inside, the open floor plan connects the living, dining, and fully equipped kitchen with an island and dining table. Entertainment and connectivity are supported with Wi‑Fi and six TVs, including one on the lanai. Outdoor living centers on a private heated pool and jacuzzi/hot tub, plus a grill, outdoor dining setup, and sun loungers. Practical conveniences include self check-in via lock box, a washer/dryer, garage parking, and family items such as a highchair and Pack n Play travel crib. Beach essentials like chairs, towels, and an umbrella are also provided.

Good fit for

Boating Fishing Family Vacations

Waterfront canal basin Set on a wide canal basin with a western-facing lanai and water views.

Gulf access Direct Gulf access is listed as under 20 minutes.

Private heated pool Private pool with electric heater plus a jacuzzi/hot tub.

Boat dock Boat dock on site with a boat lift available.

Sleeps eight 4 bedrooms and 3 bathrooms accommodate up to 8 guests.

Waterfront - ViewLocation Setting

Near a BeachBeach Access

4 BedroomsBedrooms

3 Full BathroomsBathrooms

Sleeps 8Guest Capacity

2200 sq. ft.Living Space

Pool (Private)Pool

Internet AccessInternet

TelevisionTelevision

YesAir Conditioning

YesWasher / Dryer

Cape Coral Florida

5212 Sw 22nd Place, Cape Coral Florida 33914

Location & nearby Explore the Area

Avida Serena is located in Cape Coral, Florida (South Gulf Coast) in the SW Cape Coral area. The home is set on the water along a canal basin and is described as having direct Gulf access in under 20 minutes. The setting emphasizes waterfront views from the western-facing lanai and on-the-water activities such as boating and fishing from the seawall.

Cape Coral Vacation Rentals Cape Coral Travel Guide Beyond the Canals | Hidden Mangrove Forests Cape Coral Burrowing Owls Cape Coral's 400 Miles of Canals

Rates from

$231 per night

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Season	Nightly	Weekly	Monthly
2026 Nov 01, 2026 - Nov 19, 2026	$292	n/a	n/a
2026 Nov 20, 2026 - Nov 30, 2026	$358	n/a	n/a
2026 Dec 01, 2026 - Dec 18, 2026	$292	n/a	n/a
2026 Dec 19, 2026 - Jan 07, 2027	$495	n/a	n/a
2027 Jan 08, 2027 - Jan 31, 2027	$358	n/a	n/a
2027 Feb 01, 2027 - Mar 31, 2027	$495	n/a	n/a
2027 Apr 01, 2027 - Apr 30, 2027	$358	n/a	n/a
2027 May 01, 2027 - May 23, 2027	$275	n/a	n/a
2027 May 24, 2027 - May 30, 2027	$358	n/a	n/a
2027 May 31, 2027 - Jun 30, 2027	$275	n/a	n/a
2027 Jul 01, 2027 - Jul 07, 2027	$358	n/a	n/a
2027 Jul 08, 2027 - Aug 31, 2027	$275	n/a	n/a
2027 Sep 01, 2027 - Oct 31, 2027	$231	n/a	n/a
2027 Nov 01, 2027 - Nov 18, 2027	$292	n/a	n/a
2027 Nov 19, 2027 - Nov 30, 2027	$358	n/a	n/a
2027 Dec 01, 2027 - Dec 18, 2027	$292	n/a	n/a
2027 Dec 19, 2027 - Jan 09, 2028	$495	n/a	n/a
2028 Jan 10, 2028 - Jan 31, 2028	$358	n/a	n/a
2028 Feb 01, 2028 - Apr 17, 2028	$495	n/a	n/a
2028 Apr 18, 2028 - Apr 30, 2028	$358	n/a	n/a
2028 May 01, 2028 - May 25, 2028	$275	n/a	n/a
2028 May 26, 2028 - May 29, 2028	$358	n/a	n/a
2028 May 30, 2028 - Jun 30, 2028	$275	n/a	n/a
2028 Jul 01, 2028 - Jul 08, 2028	$358	n/a	n/a

Other Availability Information

House available for rent with 4 bedrooms and 3 bathrooms that sleeps 8 in Cape Coral, FL.

Avida Serena is a waterfront Cape Coral home designed around canal views and outdoor living. The property offers 4 bedrooms, 3 full bathrooms, and accommodations for up to 8 guests across approximately 2,200 square feet. It sits on a wide canal basin and provides direct Gulf access in under 20 minutes, with a boat dock and a boat lift available.

The interior is arranged with a bright, open plan that links the main living area to the dining space and kitchen. The kitchen is equipped for everyday cooking and longer stays, with a refrigerator and ice maker, stove, oven, microwave, dishwasher, freezer, blender, toaster, cookware, spices, and serving items such as wine glasses and a baking sheet. A kitchen island and dining table support shared meals, and essentials like heating, air conditioning, ceiling fans, hangers, and extra pillows and blankets are included.

Sleeping is organized across two main suites with en-suite bathrooms plus two additional bedrooms. The listed bed setup includes 1 king, 2 queens, and 2 twin singles. For entertainment and downtime, the home provides Wi‑Fi and six TVs, including one on the lanai.

Outside, the western-facing lanai is set up for swimming, lounging, and dining. Amenities include a private pool with an electric heater, a jacuzzi/hot tub, outdoor seating, an outdoor dining area, and a grill. The private yard/garden space and terrace/patio areas extend the outdoor options, and guests can fish from the seawall or watch boats pass by. Additional conveniences include self check-in with a lock box, washer/dryer, garage/parking, bicycles available, and family-friendly items such as a highchair and Pack n Play travel crib.

Welcome to Avida Serena

Avida Serena is a breathtaking four-bedroom, three-bathroom luxury villa located in the highly desirable SW Cape Coral with direct Gulf access and walking distance to restaurants, shops, and Cape Harbor's vibrant scene, it’s the perfect spot to relax, explore, and make unforgettable memories.
From the moment you step through the elegant double glass doors, you'll be greeted by expansive living spaces and stunning views over a wide canal basin. Enjoy spectacular sunsets and watch boats drift by – all from the privacy of your own western-facing lanai.
This spacious home features two main suites, each with en-suite bathrooms, and is designed for comfort and style. The layout is perfect for families or groups of up to 8 guests, with one king suite including a cozy sitting area, a queen suite with direct patio access, and two additional bedrooms (one with twin beds, one with a queen bed).
Avida Serena is thoughtfully designed with a bright, open floor plan and modern amenities throughout. The large, fully equipped kitchen and generous living and dining areas make entertaining a breeze – whether you’re cooking together, relaxing with a movie, or enjoying quality time with loved ones.

Highlights of the outside include: a large lanai waiting to be used for sunbathing, grilling, lounging, al fresco dining with a large table, entertaining, swimming in the heated pool, enjoying the jacuzzi or just relaxing and watching unforgettable sunsets.
You can fish right off the seawall or just watch the passing by boats.
Avida Serena truly has it all. With over four-hundred miles of canals, a plethora of restaurants, nature reserves, and nearby beach towns, this location offers a wide range of activities to suit every guest.
Avida Serena as well as Vesteva welcomes you and your family to SW Florida!

Amenities:
- 4 bedrooms (1 King, 2 Queen, 2 Twin Single)
- 3 bathrooms
- Pool: Western Exposure
- Jacuzzi & Pool
- Electric pool heater
- TVs 6 (Bedroom 1, Bedroom 2, Bedroom 3, Bedroom 4, Livingroom, TV on Lanai)
- Wi-Fi
- Dining Room and Island
- Washer & dryer
- Hair dryer
- Fridge with ice maker
- Fully equipped kitchen
- Iron & ironing board
- Outside dining seats + Lounge set
- Outdoor Grill
- Keurig coffee maker

This property provides access to the following activities and special interests:

Beach

Biking

Boating

Canoeing

Casino

Deep Sea Fishing

Family Vacations

Fishing

Fly Fishing

Golfing

Horseback Riding

Kayaking

Luxury

Ocean

Sailing

Scuba Diving

Spa

State National Parks

Surfing

Wind Surfing

Other Activities and Special Interests

Basketball Court

Ice Skating

Swimming

Tennis

Watersports nearby

Tennis courts nearby

Churches

Library

Marina

Museums

Playground

Restaurants

Water Parks

Zoo

Antiquing

Bird Watching

Eco Tourism

Outlet Shopping

Walking

Bowling

Shelling

Shopping

Water Sports

Wildlife Viewing

Horse riding nearby

Featured Amenities

Air Conditioning

Dishwasher

Fireplace

Grill

Hot Tub

Internet Access

Pool (Private)

Television

Washer/Dryer

Suitability

Children Welcome

Property Features

Blender

Ceiling Fan(s)

Coffee Maker

Dishes/Utensils

Freezer

Garage

Hair Dryer

Highchair

Ice Maker

Iron / Ironing Board

Lanai

Microwave

Oven

Parking

Refrigerator

Spices

Stove

Toaster

Towels/Linens

Outdoor

Beach Chairs

Beach Towels

Beach Umbrella

Bicycle

Boat Dock

Garden

Other Property Amenities

Boat Lift Available

Cooler

Keurig Coffee Maker

Gulf Access under 20 minutes

Laptop Friendly

Jacuzzi

Kitchen

Dining Area

Kettle

Cooking Basics

Wine glasses

Baking sheet

Dining table

Cleaning products

Kitchen island

Heating

Living Room

Hangers

Essentials

Private Entrance

Self Check-In

Lock Box

Extra Pillows And Blankets

Private yard

Terrace

Bicycles available

Patio

Balcony/Terrace

Patio Or Balcony

Garden Or Backyard

Beach Essentials

Veranda

Outdoor seating

Number of spaces for outdoor dining area (integer from 1 to 100)

Sun loungers

Nearby lake

river

other body of water

Tumble dryer

Bathtub

High Chair

Pack n Play Travel Crib

Excellent

Monna

This home is beautiful and I highly recommend. It's decorated nicely and very clean. The home is stocked with all essentials plus many extras. There are many pool floats to enjoy the gorgeous pool. The lanai has comfy furniture so it's the perfect spot for those who need shade. They even have beach tent, chairs and toys to use. It's close enough to both Ft. Myers beach and Sanibel Island so we could go to both. We definitely will be back!

07/07/2026

Excellent

Carlos

Our family of four stayed at this home for a long weekend, and it exceeded our expectations! The house was absolutely beautiful, clean, and very well maintained. The kitchen was fully stocked with everything we needed to prepare meals, and the thoughtful extras like beach toys and beach essentials made our stay even more enjoyable. The pool was fantastic and a favorite spot for our family to relax after a day at the beach. One of the highlights of our trip was watching the sunset from the private boat dock—it was absolutely breathtaking and made for the perfect ending to each day. We couldn't have asked for a better place to stay and will definitely be booking this property again. Highly recommend it to anyone looking for a relaxing and well-equipped vacation home!

07/05/2026

Excellent

Steve & Ally

We had the opportunity to spend a long weekend at Avida Serena in Cape Coral. This was a needed getaway and the property/area met all of our needs. This house is immaculate. The bathrooms and kitchen are flawless and clean. The bedrooms are spacious and sleep comfortably. There is a nice living area. Being in Florida, the highlight for us was spending time in the covered pool area and patio. We also made use of the blackstone. The area is quiet and peaceful to relax in the yard. We saw several boats moving through the canal but never heard significant noise. The area is very quiet and great for evening walks, runs, bike rides. Keep count of the bunnies on those walks!

04/27/2026

incredible stay at Avida Serena

Todd & Gennie

We had an absolutely incredible stay at Avida Serena—this place truly exceeded every expectation. From the moment we arrived, it was clear how much care and attention Todd and Gennie put into this property. The home was spotless, beautifully maintained, and designed with a modern, upscale feel that instantly made us feel relaxed and at home. Every detail felt intentional, from the stylish décor to the thoughtful layout. The amenities are where this place really shines. The pool with the waterfall is stunning—perfect for both relaxing and having fun. We spent so much time outside enjoying the peaceful waterfront setting. The private dock and boat lift were a huge bonus, and having fishing gear available made it even better. It's truly a dream setup if you love being on the water. Inside, everything is top-tier. The kitchen is fully equipped with high-end appliances, making it easy to cook meals just like at home. The beds were incredibly comfortable—everyone in our group kept commenting on how well they slept—and having smart TVs in every bedroom was a great added touch for unwinding at night. The location is ideal: tucked away in a quiet, peaceful neighborhood, yet just minutes from great restaurants and easy access to both downtown Cape Coral and Fort Myers. It's the perfect balance of convenience and tranquility. Overall, Avida Serena delivers the perfect mix of luxury, comfort, and fun. Whether you're looking for a relaxing getaway or a place to enjoy the water and nearby attractions, this home has it all. We can't say enough good things about our stay and would absolutely come back again. Highly, highly recommend!

03/22/2026